The DPA is thrilled to announce the launch of Season 2 of Beyond The Scope, a podcast focusing on the hot topics in digital pathology. Co-hosts Dr. Giovanni Lujan (OSUWMC) and Dr. David Tulman (Instapath) converse with the key opinion leaders in an engaging format discussing all of the new research, technology, and workflows emerging in digital pathology. Beyond The Scope aims to cover specific topics ranging from artificial intelligence to computational pathology, whole slide imaging to in/ex-vivo microscopy, regulation and commercialization, and more!
If you are interested in being a guest on Beyond The Scope, or have requests for topics the podcast should cover, please submit the request form, HERE.
S2 E4 - Eric Glassy, MD | APMG (posted May, 2022)
As one of the earliest adopters of digital pathology, Eric Glassy has been at the forefront of most of the major DP/AI innovations in the past 25 years. Eric joins Beyond The Scope to guide us through his career long journey with digital pathology. Serving on numerous boards and committees for organizations like the DPA, CAP, and API, Eric also discusses all of the work related to the CMS waiver for remote sign out (including where we currently stand today). Eric is the Medical Director of Affiliated Pathology Medical Group, a community pathology practice primarily serving Southern California. Therefore, he appropriately presents the benefits and perils of using DP/AI in the community setting.
S2 E3 - S. Joseph Sirintrapun, MD | MSKCC (posted May 2022)
Dr. Joe Sirintrapun is a surgical pathologist and genitourinary tumor expert, currently serving as the Director of Pathology Informatics at MSKCC. Joe joins Beyond the Scope to discuss his journey to the current role at MSKCC, revealing the value of overcoming setbacks and defining some of the qualities needed to be a leader in the field of Informatics. Previously the President of The Association for Pathology Informatics (API), Joe talks about all of the work that was involved in the CLIA relaxation of regulation for remote sign-out and gives a status update about how long this may last. The 2022 API Summit is being held May 9-12 in Pittsburgh, PA. Please click here for more information.
Dr. Jason Hipp is the Chair of the Division of Computational Pathology and Artificial Intelligence at the Mayo Clinic and the Director of Digital Innovation for Mayo Reference Labs. Jason joins Beyond the Scope to discuss his career path, which includes work in academia, the NCI, big pharma, and big tech. His journey through an evolving digital pathology industry is paving the way for pathologists to occupy non-traditional roles, such as informatics director or clinical trials pathologist. Additionally, the conversation touches on some of the current hot topics in computational pathology and artificial intelligence.
S2 E1 - Jonhan Ho, MD | UPMC (posted April 2022)
Season 2 of Beyond the Scope kicks off with a conversation with Jon Ho, dermatopathologist and founder of Kiko, a social media platform made to connect physicians. Dr. Ho discusses his passion for education and ways his department at UPMC are using digital pathology and artificial intelligence for both research and education.
David Klimstra is the Chief Medical Officer at Paige and was previously the Chair of Pathology at Memorial Sloan Kettering Cancer Center. Paige is a medical company offering the first FDA cleared artificial intelligence platform to assist with the diagnosis of prostate cancer. Dr. Klimstra joins the show to discuss building a robust digital pathology program at MSKCC and the transition from academia to industry. Furthermore, he offers insights into what the first FDA clearance for an AI product means to the industry and the overall breadth of AI applications in pathology.
S1 E16 - Sylvia Asa, MD, PhD | University Hospitals Cleveland (posted October 2021)
Sylvia Asa is an endocrine pathologist leading University Hospitals in Cleveland, OH into the era of digital pathology. Previously, Dr. Asa was the Head of Pathology at Canada's largest hospital network, where she successfully built a digital pathology workflow. She joins Beyond The Scope to discuss the moment of realizing the power of digitizing a slide to achieving a fully integrated digital pathology workflow in Canada's largest medical network. As a Chair of the upcoming DPA Visions Conference (October 17-19 at the MGM Grand in Las Vegas), she previews the program and highlights some of the upcoming talks. Finally, Dr. Asa gives her thoughts on what the field of pathology may look like in 10-20 years.
S1 E15 - Single-center COVID-19 remote sign out experience, featuring medical student correspondent Harrison Dai (posted September 2021)
Beyond the Scope returns as David and Giovanni discuss a publication from Archives of Pathology and Laboratory Medicine: "Digital Pathology Initiatives and Experience of a Large Academic Institution During the Coronavirus Disease 2019 (COVID-19) Pandemic". Topics include process to establish a 100% digital workflow, the remote validation process, and how the workflow was also useful for research and education. (24:49) Then, Harrison Dai (MS2, Eastern Virginia University) joins the show in a new segment sharing his experience as a medical student during the pandemic, in addition to the medical student perspective on digital pathology.
S1 E14 - Raj Singh, MD | Northwell & Matthew Hannah, MD | MSKCC (posted August 2021)
Raj and Matt join Beyond the Scope to discuss the the Digital Anatomic Pathology Academy, hosted on PathPresenter - a primarily open source cloud based viewing platform for digital slides. DAPA is used as an educational, clinical, and publication tool. DPA members can access DAPA for free to make use of the numerous educational modules (dpa-dapa.com).
- 2:48 Guest intro
- 7:21 Introduction to the cloud based viewing and educational platform
- 8:47 Tutorial for navigating the platform
- 17:20 DAPA educational module features and demonstration
- 20:45 DAPA use cases; including an interactive way to study for boards
- 26:00 How DPA members and other can access the platform
- 27:50 Open source platform vs. licensed version for private data
- 30:10 MSKCC experience using the platform as an education portal and conference tool
- 33:00 Long term clinical goals of the platform
- 37:55 Utilizing the platform in underserved areas
- 39:23 Utilizing the platform for publications and E-books
S1 E13 - Marilyn M. Bui, MD, PhD, FCAP | Moffitt Cancer Center (posted July 2021)
Marilyn M. Bui, MD, PhD, FCAP is a senior member in the Department of Pathology at Moffitt Cancer Center where she serves as the scientific director of the Analytic Microscopy Core. She has previously served as president of the DPA and currently chairs many committees for CAP and DPA. Dr. Bui joins Beyond the Scope to discuss her work toward digital pathology adoption and building a connected network of pathologists.
- 1:58 Introduction and what it means to be a pathologist in the digital age
- 6:03 Evolution of pathology toward the digital era
- 10:18 How experience as a molecular biology researcher led to a career focused on DP/AI
- 14:25 Building relationships through the DPA and how to get involved
- 18:24 Highlights throughout the years of DPA leadership
- 22:34 Global digital pathology collaborations
- 24:23 DAPA - a cloud based platform for DP education
- 31:05 Using social media to promote DP adoption and education
- 32:47 Digital health initiatives at Moffitt Cancer Center
- 36:33 Current research projects in DP/AI
- 41:55 The future of pathology - how to improve the workforce,promote a healthy lifestyle, and decrease the workload
S1 E12 - Chen Sagiv, PhD | DeePathology (posted June 2021)
Chen Sagiv is an entrepreneur and computer scientist. She joins Beyond the Scope to discuss her story as a co-founder of DeePathology, a start-up providing AI tools for pathologists, as well as the challenges and excitement surrounding innovation in the digital pathology industry.
- 3:01 Introduction
- 7:29 Early applications of computer science in healthcare and why deep learning/AI methods are mandatory knowledge for modern computer scientists
- 11:15 The importance of cross disciplinary work between engineers, pathologists, and computer scientists
- 18:15 Story behind DeePathology and how the start-up helps pathologists use and understand AI tools
- 25:47 The perceived "black box" of AI vs. DIY AI platforms
- 31:50 Building AI algorithms from scratch
- 37:19 Advice for innovators in the pathology space
S1 E11 - David Clunie, MD | PixelMed Publishing (posted June 2021)
Dr. David Clunie is a radiologist, medical informaticist, DICOM open source software author and editor of the DICOM standard. He joins Beyond The Scope to discuss image format standards surrounding digital pathology adoption. For more information, please visit: https://www.dclunie.com/.
- 3:00 Introduction
- 4:15 Background on PACS and DICOM, and the importance to pathology
- 6:39 History of DICOM as the image standard for radiology
- 10:04 Why an image standard has yet to emerge for pathology
- 15:38 How pathology departments can work with IT departments to aid the digital transition
- 16:54 Clarifying misconceptions about PACS
- 21:52 Discussing all cost elements associated with digital pathology transition
- 27:43 Advice to pathologists regarding image archival standards long term
- 33:20 Collaborative efforts between pathology, radiology, and IT departments
- 37:22 Education the pathology community on image standards and regulatory barriers
- 44:51 The role of enterprise IT in DP adoption
S1 E10 - Raisa Glabman, MSPH, VMD | NIH NCI CBSTP Fellow (posted May 2021)
Raisa Glabman is a veterinary pathologist and a fellow in the NIH/NCI Comparative Biomedical Scientist Training Program (CBSTP). Raisa joins Beyond the Scope to discuss her research on immunotherapy and the tumor microenvironment, how researchers in her field are using DP/AI, and the current state of DP adoption in veterinary medicine.
- 2:28 Introduction
- 4:37 NCI CBSTP program
- 9:00 Why veterinary pathology is interested in DP/AI for clinical and research applications
- 12:45 What human and veterinary pathologists can learn from each other regarding DP adoption
- 16:30 DP applications in various veterinary pathology settings - industrial labs, academic centers, and small clinics
- 20:25 Raisa's research on immunotherapy and the tumor microenvironment
- 25:53 How Raisa is using DP/AI for her research
- 28:10 Doing research during the pandemic
- 29:43 Being an early adopter of DP/AI tools for this specific type of research
- 34:50 How DP will help researchers ask new scientific questions
S1 E9 - George Green, PhD | Bristol Myers Squibb (posted April 2021)
George Green joins Beyond the Scope to discuss the pharmaceutical industry's perspective on digital pathology and artificial intelligence. The conversation revolves around how digital pathology will see increased applications in the current era of precision medicine.
- 1:22 Introduction
- 4:15 The companion diagnostics revolution in pharma
- 9:54 Early applications of digital pathology in pharma
- 14:38 How the mindset of pathologists has evolved since the dawn of DP/AI
- 19:55 Pharma perspective on how DP/AI will drive the future of precision medicine
- 25:00 Increasing DP adoption in the pharma industry
- 28:40 Digital pathology bringing better patient care around the world
S1 E8 - Esther Abels, MSc | Visiopharm; DPA President-Elect (posted April 2021)
Esther Abels, co-chair of the DPA Regulatory & Standards Task Force, has worked on the regulatory approval of digital pathology systems since the beginning. She joins Beyond The Scope to discuss her current role advancing the regulatory science of digital pathology and provides an update on the initiatives of the DPA Regulatory and Standards Task Force. Esther also discusses the excitement surrounding digital pathology for precision medicine.
- 2:21 Introduction
- 6:25 Early applications of digital pathology to the pharma industry
- 8:00 Process of validating and achieving FDA approval of the first slide scanners
- 10:00 How collaboration and teamwork help achieve regulatory approval
- 17:48 Current initiatives of the DPA Regulatory and Standars Task Force
- 21:40 510(k) exemption of digital pathology devices
- 25:00 Real world data initiative and is remote sign out permanent?
- 31:08 Using digital pathology for precision medicine
S1 E7 - Dr. Talat Zehra, MBBS, FCPS | Jinnah Sindh Medical University, Karachi, Pakistan (posted March 2021)
Talat Zehra is a pathologist at Jinnah Sindh University in Karachi, Pakistan. Dr. Zehra joins Beyond The Scope to share how the scarcity of pathologists in Pakistan and many other regions of the world affect patient care. Dr. Zehra also discusses the advantages and challenges of bringing digital pathology to developing countries.
- 1:00 Introduction
- 3:30 Dr. Zehra's research with WSI in Pakistan
- 6:15 Pathology services in Pakistan and other developing countries
- 13:15 Pathology in rural areas of the world
- 14:33 Benefits of digital pathology in developing countries
- 17:42 Challenges of digital pathology adoption in developing countries
- 19:05 Ideas for vendors and other pathologists to help increase adoption in developing countries
Please visit other resources mentioned in this podcast:
S1 E6 - Liron Pantanowitz, MD | University of Michigan; DPA Treasurer (posted March 2021)
Liron Pantanowitz is an early adopter and major driving force behind global digital pathology adoption. He currently serves as a Professor in the Department of Pathology at the University of Michigan and has authored hundreds of papers related to digital pathology. Dr. Pantanowitz joins David and Giovanni to discuss the past, present, and future of digital pathology. This podcast is a must-listen for all levels of digital pathology adopters.
- 5:45 Introduction and background leading to a career focused on digital pathology
- 8:38 Milestones of digital pathology adoption
- 12:10 Digital pathology applications and the business case
- 15:46 The effect of COVID-19 on digital pathology adoption
- 23:23 Global digital pathology adoption
- 29:00 Training the next generation of digital pathologists
- 41:04 What's next for digital pathology
S1 E5 - Monica Santamaria-Fries, MD | Proscia (posted March 2021)
Monica Santamaria-Fries is the Digital Transformation Officer at Proscia, a role where she uses her extensive experience as a pathologist to bridge the gap in communicating novel digital pathology technology to the pathology community. Dr. Santamaria-Fries joins the show to discuss her role in digital pathology innovation, the annual digital pathology report generated by Proscia, and why the time is now for digital pathology adoption.
- 3:34 Introduction and background
- 8:50 Pathologists bridging the gap when communicating new technologies to other pathologists
- 12:04 New innovations in computation pathology and improved pathology workflow
- 19:43 Moments that trigger pathologists to want to go digital
- 27:57 Highlights of the annual digital pathology report
- 29:11 Why now is the time to go digital and how to remove roadblocks
S1 E4 - Joe Lennerz, MD, PhD | Massachusetts General Hospital (posted February 2021)
Joe Lennerz is the Director of the Center of Integrated Diagnostics at Massachusetts General Hospital and a founding member of The Alliance for Digital Pathology. Dr. Lennerz sits down with Giovanni and David to discuss innovating in the digital pathology space, regulatory science related to digital pathology, and the initiatives of The Alliance. For more resources on Dr. Lennerz's work and how to get involved with The Alliance for Digital Pathology, please click here.
- 4:38 Introduction and background
- 6:35 Implementing innovative diagnostics in clinical practice
- 20:23 Formation of The Alliance for Digital Pathology and applying regulatory science to digital pathology innovation
- 27:29 Current goals and initiatives directed by The Alliance
- 32:25 Getting involved with The Alliance and how to connect with key stakeholders in digital pathology innovation
S1 E3 - Michael Rivers | Roche; DPA Immediate Past President (posted January 2021)
Michael Rivers just completed his term as DPA president and joins David and Giovanni to discuss the numerous initiatives in which the DPA was involved while navigating COVID-19. Plus, he gives an industry perspective on the future of the digital pathology industry.
S1 E2 - Anil Parwani, MD, PhD, MBA | Ohio State University; DPA President (posted December 2020)
Dr. Anil Parwani (OSUWMC) joins the show to share why he chose to pursue a career focusing on digital pathology and gives advice to departments looking to start a digital pathology program.
Season 1 Episode 1 - An Introduction
Dr. Giovanni Lujan and Dr. David Tulman preview the concept of the podcast, discuss their backgrounds in digital pathology, and project the future of pathology.